Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5071
Gene Symbol: PRKN
PRKN 		0.100 GeneticVariation phenotype GWASCAT Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. 31560688 2019
Entrez Id: 463
Gene Symbol: ZFHX3
ZFHX3 		0.100 GeneticVariation phenotype GWASCAT Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. 31560688 2019
Entrez Id: 3992
Gene Symbol: FADS1
FADS1 		0.100 GeneticVariation phenotype GWASCAT Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. 31560688 2019
Entrez Id: 10579
Gene Symbol: TACC2
TACC2 		0.100 GeneticVariation phenotype GWASCAT Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. 31560688 2019
Entrez Id: 9415
Gene Symbol: FADS2
FADS2 		0.100 GeneticVariation phenotype GWASCAT Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. 31560688 2019
Entrez Id: 84186
Gene Symbol: ZCCHC7
ZCCHC7 		0.100 GeneticVariation phenotype GWASCAT Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain. 31560688 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		0.300 Biomarker phenotype CTD_human Moreover, adipocyte-specific EZH2 KO mice, generated by crossing EZH2 floxed mice with adiponectin-Cre mice, displayed significantly increased body weight, adipose tissue mass, and adipocyte cell size and reduced very low-density lipoprotein (VLDL) levels, as compared with littermate controls. 30971429 2019
Entrez Id: 196
Gene Symbol: AHR
AHR 		0.300 Biomarker phenotype CTD_human The data demonstrate that AHR deficiency significantly reduces weight gain and adiposity, and increases multilocular lipid droplet formation within perigonadal white adipose tissue (gWAT). 30813227 2019
Entrez Id: 284207
Gene Symbol: METRNL
METRNL 		0.300 Therapeutic phenotype CTD_human Furthermore, METRNL administration rescued glucose intolerance and reduced HFD-induced body weight gain in mice; however, METRNL did not affect calorie intake. 30213948 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker phenotype CTD_human Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates kidney injury in murine models of obesity and diabetes mellitus. 29988851 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Biomarker phenotype CTD_human Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance. 29967158 2018
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Therapeutic phenotype CTD_human Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance. 29967158 2018
Entrez Id: 55277
Gene Symbol: FGGY
FGGY 		0.300 Biomarker phenotype CTD_human Prenatal Exposure to Bisphenol A Disrupts Naturally Occurring Bimodal DNA Methylation at Proximal Promoter of fggy, an Obesity-Relevant Gene Encoding a Carbohydrate Kinase, in Gonadal White Adipose Tissues of CD-1 Mice. 29220483 2018
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker phenotype CTD_human Importance of tau in cognitive decline as revealed by developmental exposure to lead. 29203278 2018
Entrez Id: 3778
Gene Symbol: KCNMA1
KCNMA1 		0.300 Biomarker phenotype CTD_human Obesogenic and Diabetogenic Effects of High-Calorie Nutrition Require Adipocyte BK Channels. 27605626 2016
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Therapeutic phenotype CTD_human IL-33 Drives Augmented Responses to Ozone in Obese Mice. 27472835 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Biomarker phenotype CTD_human IL-33 Drives Augmented Responses to Ozone in Obese Mice. 27472835 2017
Entrez Id: 3779
Gene Symbol: KCNMB1
KCNMB1 		0.300 Biomarker phenotype CTD_human High-fat diet-induced obesity alters nitric oxide-mediated neuromuscular transmission and smooth muscle excitability in the mouse distal colon. 27288421 2016
Entrez Id: 3620
Gene Symbol: IDO1
IDO1 		0.300 Biomarker phenotype CTD_human Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. 27020609 2016
Entrez Id: 196
Gene Symbol: AHR
AHR 		0.300 Biomarker phenotype CTD_human Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. 27020609 2016
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker phenotype CTD_human Gender-specific genetic associations of polymorphisms in ACE, AKR1C2, FTO and MMP2 with weight gain over a 10-year period. 25322899 2014
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		0.300 Biomarker phenotype CTD_human We found that FTO in men and MMP2 in women are associated with weight gain over a 10-year follow-up period. 25322899 2014
Entrez Id: 79068
Gene Symbol: FTO
FTO 		0.300 Biomarker phenotype CTD_human We found that FTO in men and MMP2 in women are associated with weight gain over a 10-year follow-up period. 25322899 2014
Entrez Id: 1646
Gene Symbol: AKR1C2
AKR1C2 		0.300 Biomarker phenotype CTD_human Gender-specific genetic associations of polymorphisms in ACE, AKR1C2, FTO and MMP2 with weight gain over a 10-year period. 25322899 2014
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Biomarker phenotype CTD_human Oral administration of Nitraria retusa ethanolic extract enhances hepatic lipid metabolism in db/db mice model 'BKS.Cg-Dock7(m)+/+ Lepr(db/)J' through the modulation of lipogenesis-lipolysis balance. 25086370 2014